Category: Finance News

Gainers

• Otonomy, Inc. OTIC shares surged 74.2% to $0.1866. Otonomy recently posted a Q3 loss of $0.18 per share.
• Apollo Endosurgery, Inc. APEN shares jumped 65% to $9.90 after the company announced it will be acquired by Boston Scientific for $10 per share in cash.
• The Very Good Food Company Inc. VGFC rose 36.6% to $0.1370.
• Kalera Public Limited Company KAL gained 29% to $0.16. Kalera announced restructuring process for German subsidiary.
• Kidpik Corp. PIK gained 25.6% to $0.98.
• Citi Trends, Inc. CTRN shares climbed 24.4% to $28.87 after the company reported better-than-expected Q3 adjusted EPS and sales results.
• Cosmos Holdings Inc. COSM jumped 23.3% to $0.7157 after jumping 35% on Monday.
• Bilibili Inc. BILI gained 23.2% to $15.52 after the company reported better-than-expected Q3 adjusted EPS and sales results.
• Zhihu Inc. ZH rose 20.3% to $1.0907 after declining over 9% on Monday.
• Faraday Future Intelligent Electric Inc. FFIE climbed 19.4% to $0.3626. Faraday Future Intelligent Electric Board of Directors has appointed FF China CEO Xuefeng (XF) Chen as Global CEO of the company, effective immediately.
• GDS Holdings Limited GDS shares rose 17.3% to $13.73. The company recently posted upbeat quarterly sales.
• NRx Pharmaceuticals, Inc. NRXP jumped 16.8% to $1.46.
• Vivakor, Inc. VIVK gained 16.6% to $1.1897 after posting a narrower quarterly loss.
• United Maritime Corporation USEA rose 16.3% to $3.5108. United Maritime declared a special cash dividend of $1.00 per share.
• ThermoGenesis Holdings, Inc. THMO surged 16% to $0.1371. ThermoGenesis Holdings recently posted a Q3 loss of $0.10 per share.
• Aenza S.A.A. AENZ jumped 15.8% to $2.3750.
• Fusion Fuel Green PLC HTOO gained 15.6% to $5.64. HC Wainwright & Co. maintained Fusion Fuel Green with a Buy and lowered the price target from $25 to $15.
• Kanzhun Limited BZ rose 15.3% to $17.41 after gaining over 5% on Monday.
• Dada Nexus Limited DADA gained 15% to $5.76. Shares of several Chinese companies traded higher amid hopes that protests in China could spark an easing of COVID restrictions.
• ThermoGenesis Holdings, Inc. THMO rose 14.2% to $0.1351. ThermoGenesis recently posted a Q3 loss of $0.10 per share.
• RLX Technology Inc. RLX gained 13.8% to $2.2086.
• The GEO Group, Inc. GEO surged 12% to $11.45 following positive analyst coverage from Wedbush.
• Kingsoft Cloud Holdings Limited KC gained 11.6% to $2.6350. Shares of several Chinese companies traded higher amid hopes that protests in China could spark an easing of COVID restrictions.
• Eqonex Limited EQOS rose 10.9% to $0.1562.
• HUYA Inc. HUYA gained 10.9% to $ 2.2850. Shares of several Chinese companies traded higher amid hopes that protests in China could spark an easing of COVID restrictions.
• XPeng Inc. XPEV climbed 10.2% to $7.59. Shares of several Chinese companies traded higher amid hopes that protests in China could spark an easing of COVID restrictions.
• JD.com, Inc. JD gained 8.4% to $54.19. JD.com is looking to lower pay by up to 20% for senior executives, according to Financial Times.
• JOYY Inc. YY rose 7.2% to $29.50 following upbeat quarterly earnings.

 

Losers

• MICT, Inc. MICT fell 28.3% to $0.81 after dropping 13% on Monday. MICT said that the company is targeting a considerable share repurchase program post-merger close
• Alaunos Therapeutics, Inc. TCRT shares fell 24.2% to $0.6575 after the company reported pricing of public offering of common stock.
• Satixfy Communications Ltd. SATX dropped 17.4% to $16.82.
• Enfusion, Inc. ENFN declined 16.7% to $10.24. Enfusion announced resignation of chief financial officer and reiterated Q4 and FY22 outlook.
• Digital Brands Group, Inc. DBGI declined 15.9% to $6.05.
• ASAP, Inc. ASAP fell 15.7% to $0.9101. ASAP.com & Chipotle Mexican Grill signed major food delivery agreement.
• NanoVibronix, Inc. NAOV shares fell 15.5% to $0.5349 after the company announced a $2.4 million registered direct offering priced at-the-market under Nasdaq rules.
• AGBA Group Holding Limited AGBA fell 14.5% to $2.94.
• FOXO Technologies Inc. FOXO fell 13.8% to $0.4785 after dropping around 10% on Monday.
• Coeptis Therapeutics Holdings, Inc. COEP shares fell 13.7% to $1.7699.
• CinCor Pharma, Inc. CINC fell 13.4% to $12.23. Oppenheimer downgraded CinCor Pharma from Outperform to Perform, while Morgan Stanley downgraded the stock from Overweight to Equal-Weight and lowered the price target from $60 to $22.
• Hibbett, Inc. HIBB fell 12.2% to $59.33 after the company reported worse-than-expected Q3 EPS and sales results.
• CNS Pharmaceuticals, Inc. CNSP fell 11.7% to $4.4250. CNS Pharmaceuticals announced a 1-for-30 reverse stock split.
• Ainos, Inc. AIMD declined 11.6% to $0.6101. Ainos posted Q3 loss of $0.51 per share.
• Nutex Health Inc. NUTX dropped 10.3% to $1.39.
• Elbit Systems Ltd. ESLT fell 9.2% to $169.67 after the company reported a drop in profit for the third quarter.
• Sprout Social, Inc. SPT dipped 7.7% to $53.40.

© 2022 Benzinga.com. Benzinga does not provide investment advice. All rights reserved.

Gainers

• Taboola.com Ltd. TBLA shares gained 52.5% to $2.8050 after the company announced it entered into a 30-year exclusive commercial agreement with Yahoo.
• Digital Brands Group, Inc. DBGI shares jumped 47.8% to $8.81. The company recently posted a rise in Q3 revenue.
• NanoVibronix, Inc. NAOV gained 39% to $0.3599. NanoVibronix recently announced interim results of its U.K. clinical study for UroShield, a disposable ultrasound device that reduces biofilm contaminating the catheter surface.
• Talkspace, Inc. TALK shares climbed 34.3% to $0.8055. Talkspace recently named Jon Cohen as CEO.
• Studio City International Holdings Limited MSC gained 33% to $2.70.
• Helbiz, Inc. HLBZ rose 31.8% to $0.3032 after gaining more than 21% on Friday.
• Axsome Therapeutics, Inc. AXSM climbed 31.4% to $74.71 after the company announced AXS-05 achieved its primary endpoint in the ACCORD Phase 3 trial in Alzheimer’s disease agitation.
• Tricida, Inc. TCDA rose 25.3% to $0.2577 after gaining over 6% on Friday.
• Kintara Therapeutics, Inc. KTRA shares gained 23% to $4.5375 after the company announced it was granted Fast Track Designation from the FDA for REM-001 for cutaneous Metastatic Breast Cancer.
• So-Young International Inc. SY jumped 21% to $0.7705. The company recently posted downbeat quarterly sales.
• Bit Brother Limited BTB gained 19.2% to $0.26.
• Katapult Holdings, Inc. KPLT gained 18.8% to $1.14. Katapult recently appointed Nancy Walsh as new CFO.
• Cosmos Holdings Inc. COSM surged 18.4% to $0.5077.
• Recruiter.com Group, Inc. RCRT rose 17.4% to $0.4345. Recruiter.com Group, on November 18th, said it received a notification letter from the Nasdaq Listing Qualifications Staff of the Nasdaq Stock Market LLC.
• Biophytis S.A. BPTS gained 16.3% to $0.4472.
• Centogene N.V. CNTG jumped 15.7% to $0.88. HC Wainwright & Co. recently initiated coverage on Centogene with a Buy rating and announced a price target of $2.5.
• Pinduoduo Inc. PDD gained 14% to $75.03. Pinduoduo reported third-quarter FY22 revenue growth of 65% year-on-year to $4.99 billion, beating the consensus of $4.31 billion.
• Standard BioTools Inc. LAB surged 13.8% to $1.48. Standard BioTools authorized up to $20 million in share repurchases.
• HUTCHMED (China) Limited HCM gained 12.4% to $12.03.
• The Singing Machine Company, Inc. MICS shares rose 12.3% to $6.17. Singing Machine recently posted Q2 EPS of $0.08.
• BiomX Inc. PHGE jumped 11.5% to $0.28. The company recently posted a narrower quarterly loss.
• Lion Group Holding Ltd. LGHL gained 11.4% to $1.27.
• Abcam plc ABCM rose 10.2% to $17.48. NanoString and Abcam recently expanded collaboration to advance spatial multiomics research.
• American Rebel Holdings, Inc. AREB rose 9.7% to $0.2843 after gaining over 8% on Friday. The company recently posted a narrower quarterly loss.
• Tencent Music Entertainment Group TME gained 8.7% to $6.28. JP Morgan recently upgraded Tencent Music Enter from Neutral to Overweight and raised the price target from $4.8 to $7.7.
• Dada Nexus Limited DADA gained 6.8% to $4.97.
• Univar Solutions Inc. UNVR rose 5.2% to $32.62 after the company confirmed preliminary indication of interest from Brenntag SE.

Losers

• CinCor Pharma, Inc. CINC shares dipped 46.9% to $14.08 after the company announced topline data for the Phase 2 HALO trial evaluating Baxdrostat in uncontrolled hypertension. HALO did not achieve statistical significance on its primary endpoint.
• OncoSec Medical Incorporated ONCS fell 22.6% to $2.60. OncoSec Medical recently announced early clinical data from an investigator-sponsored trial of TAVO in combination with Bristol-Myers Squibb Co’s BMY intravenous Opdivo (nivolumab).
• Troika Media Group, Inc. TRKA dropped 21.4% to $0.1831.
• TC Biopharm (Holdings) Plc TCBP dipped 21% to $5.30 after the company announced a $7.35 million private placement.
• Golden Sun Education Group Limited GSUN fell 18% to $1.6901.
• EUDA Health Holdings Limited EUDA dropped 17.6% to $3.0401.
• Anavex Life Sciences Corp. AVXL fell 17.3% to $9.83 after the company reported worse-than-expected Q4 EPS results.
• Bioventus Inc. BVS fell 15.5% to $2.0712. The company recently posted downbeat quarterly results.
• Evolve Transition Infrastructure LP SNMP dropped 15.5% to $0.1521.
• Peraso Inc. PRSO declined 15.4% to $1.15. Peraso announced a $2.45 million registered direct offering.
• Peak Bio, Inc. PKBO dropped 14.8% to $5.42.
• Scilex Holding Company SCLX shares fell 14.6% to $4.11.
• TransCode Therapeutics, Inc. RNAZ dipped 13.7% to $0.4140. TransCode Therapeutics filed for offering of up to 12.5 million shares of common stock on firm commitment basis.
• Expion360 Inc. XPON dropped 13.6% to $1.27. Expion360 recently posted a Q3 loss of $0.19 per share.
• Grindr Inc. GRND fell 13.4% to $8.27.
• Community Health Systems, Inc. CYH fell 13% to $3.1150.
• The Hain Celestial Group, Inc. HAIN dipped 12.6% to $18.05. Hain Celestial Group appointed Wendy P. Davidson as President and Chief Executive Officer, effective January 1, 2023.
• Satixfy Communications Ltd. SATX fell 11.7% to $20.21.
• Brenmiller Energy Ltd BNRG fell 11.7% to $1.5101 after jumping 14% on Friday.
• Fluence Energy, Inc. FLNC dropped 11.5% to $16.42.
• NewAmsterdam Pharma Company N.V. NAMS shares fell 10.6% to $9.00.
• Prime Medicine, Inc. PRME dipped 10.2% to $18.60.
• Polestar Automotive Holding UK PLC PSNY dropped 8.8% to $7.29.
• Check-Cap Ltd. CHEK dipped 8.8% to $3.5005.
• Cyxtera Technologies, Inc. CYXT fell 8.7% to $1.7050.
• DraftKings Inc. DKNG fell 3.7% to $14.59. JP Morgan downgraded DraftKings from Neutral to Underweight and announced $12 price target.

© 2022 Benzinga.com. Benzinga does not provide investment advice. All rights reserved.

Gainers

• Otonomy, Inc. OTIC shares surged 74.2% to $0.1866. Otonomy recently posted a Q3 loss of $0.18 per share.
• Apollo Endosurgery, Inc. APEN shares jumped 65% to $9.90 after the company announced it will be acquired by Boston Scientific for $10 per share in cash.
• The Very Good Food Company Inc. VGFC rose 36.6% to $0.1370.
• Kalera Public Limited Company KAL gained 29% to $0.16. Kalera announced restructuring process for German subsidiary.
• Kidpik Corp. PIK gained 25.6% to $0.98.
• Citi Trends, Inc. CTRN shares climbed 24.4% to $28.87 after the company reported better-than-expected Q3 adjusted EPS and sales results.
• Cosmos Holdings Inc. COSM jumped 23.3% to $0.7157 after jumping 35% on Monday.
• Bilibili Inc. BILI gained 23.2% to $15.52 after the company reported better-than-expected Q3 adjusted EPS and sales results.
• Zhihu Inc. ZH rose 20.3% to $1.0907 after declining over 9% on Monday.
• Faraday Future Intelligent Electric Inc. FFIE climbed 19.4% to $0.3626. Faraday Future Intelligent Electric Board of Directors has appointed FF China CEO Xuefeng (XF) Chen as Global CEO of the company, effective immediately.
• GDS Holdings Limited GDS shares rose 17.3% to $13.73. The company recently posted upbeat quarterly sales.
• NRx Pharmaceuticals, Inc. NRXP jumped 16.8% to $1.46.
• Vivakor, Inc. VIVK gained 16.6% to $1.1897 after posting a narrower quarterly loss.
• United Maritime Corporation USEA rose 16.3% to $3.5108. United Maritime declared a special cash dividend of $1.00 per share.
• ThermoGenesis Holdings, Inc. THMO surged 16% to $0.1371. ThermoGenesis Holdings recently posted a Q3 loss of $0.10 per share.
• Aenza S.A.A. AENZ jumped 15.8% to $2.3750.
• Fusion Fuel Green PLC HTOO gained 15.6% to $5.64. HC Wainwright & Co. maintained Fusion Fuel Green with a Buy and lowered the price target from $25 to $15.
• Kanzhun Limited BZ rose 15.3% to $17.41 after gaining over 5% on Monday.
• Dada Nexus Limited DADA gained 15% to $5.76. Shares of several Chinese companies traded higher amid hopes that protests in China could spark an easing of COVID restrictions.
• ThermoGenesis Holdings, Inc. THMO rose 14.2% to $0.1351. ThermoGenesis recently posted a Q3 loss of $0.10 per share.
• RLX Technology Inc. RLX gained 13.8% to $2.2086.
• The GEO Group, Inc. GEO surged 12% to $11.45 following positive analyst coverage from Wedbush.
• Kingsoft Cloud Holdings Limited KC gained 11.6% to $2.6350. Shares of several Chinese companies traded higher amid hopes that protests in China could spark an easing of COVID restrictions.
• Eqonex Limited EQOS rose 10.9% to $0.1562.
• HUYA Inc. HUYA gained 10.9% to $ 2.2850. Shares of several Chinese companies traded higher amid hopes that protests in China could spark an easing of COVID restrictions.
• XPeng Inc. XPEV climbed 10.2% to $7.59. Shares of several Chinese companies traded higher amid hopes that protests in China could spark an easing of COVID restrictions.
• JD.com, Inc. JD gained 8.4% to $54.19. JD.com is looking to lower pay by up to 20% for senior executives, according to Financial Times.
• JOYY Inc. YY rose 7.2% to $29.50 following upbeat quarterly earnings.

 

Losers

• MICT, Inc. MICT fell 28.3% to $0.81 after dropping 13% on Monday. MICT said that the company is targeting a considerable share repurchase program post-merger close
• Alaunos Therapeutics, Inc. TCRT shares fell 24.2% to $0.6575 after the company reported pricing of public offering of common stock.
• Satixfy Communications Ltd. SATX dropped 17.4% to $16.82.
• Enfusion, Inc. ENFN declined 16.7% to $10.24. Enfusion announced resignation of chief financial officer and reiterated Q4 and FY22 outlook.
• Digital Brands Group, Inc. DBGI declined 15.9% to $6.05.
• ASAP, Inc. ASAP fell 15.7% to $0.9101. ASAP.com & Chipotle Mexican Grill signed major food delivery agreement.
• NanoVibronix, Inc. NAOV shares fell 15.5% to $0.5349 after the company announced a $2.4 million registered direct offering priced at-the-market under Nasdaq rules.
• AGBA Group Holding Limited AGBA fell 14.5% to $2.94.
• FOXO Technologies Inc. FOXO fell 13.8% to $0.4785 after dropping around 10% on Monday.
• Coeptis Therapeutics Holdings, Inc. COEP shares fell 13.7% to $1.7699.
• CinCor Pharma, Inc. CINC fell 13.4% to $12.23. Oppenheimer downgraded CinCor Pharma from Outperform to Perform, while Morgan Stanley downgraded the stock from Overweight to Equal-Weight and lowered the price target from $60 to $22.
• Hibbett, Inc. HIBB fell 12.2% to $59.33 after the company reported worse-than-expected Q3 EPS and sales results.
• CNS Pharmaceuticals, Inc. CNSP fell 11.7% to $4.4250. CNS Pharmaceuticals announced a 1-for-30 reverse stock split.
• Ainos, Inc. AIMD declined 11.6% to $0.6101. Ainos posted Q3 loss of $0.51 per share.
• Nutex Health Inc. NUTX dropped 10.3% to $1.39.
• Elbit Systems Ltd. ESLT fell 9.2% to $169.67 after the company reported a drop in profit for the third quarter.
• Sprout Social, Inc. SPT dipped 7.7% to $53.40.

© 2022 Benzinga.com. Benzinga does not provide investment advice. All rights reserved.

Overview

WHO plays a major role in the cycle of supply chain management for donated and/or
procured health products for neglected tropical diseases (NTDs) amenable to preventive
chemotherapy and individual case management.
This first edition describes the standard operating procedures for health products for NTDs
amenable to preventive chemotherapy and the medicines donated to treat them. These
include albendazole for lymphatic filariasis and soil-transmitted helminthiases; azithromycin
for trachoma and yaws; diethylcarbamazine citrate for lymphatic filariasis; ivermectin for
onchocerciasis and lymphatic filariasis; mebendazole for soil-transmitted helminthiases;
praziquantel for schistosomiasis; and triclabendazole for foodborne trematodiases.
Standard operating procedures for diseases amenable to case management will be
covered in subsequent editions, including the application process for requesting medicines
(Chapter 1). In the meantime, the procedures described in the rest of the document apply
for both case management and preventive chemotherapy NTD health products.
WHO and the NTD Supply Chain Forum prepared this set of standard operating procedures
to reflect key characteristics in the supply chain management of health products including
donated medicines for use in mass drug administration (MDA) at the country level. Health
ministries and national programmes for NTDs are encouraged to adopt and adapt them to
their country context.

The role of the supply chain in MDA

MDA plays a role in the primary prevention of NTDs amenable to preventive chemotherapy
by decreasing transmission rates in populations at risk. The effectiveness of the MDA
strategy depends on epidemiological coverage, which is defined by WHO-recommended
targets for the proportion of the total population ingesting the medicines during MDA.
In order to meet the coverage targets the supply chain must be managed, from planning
and quantifying needs, to moving stock from production sites to patients at the service
delivery point to communities, schools and hospitals, among others, and to retrieving and
accounting for leftover stock, and all steps in between.

Objectives of these standard operating procedures

These standard operating procedures are intended to help strengthen the capacity of
health ministries and national NTD programmes to mainstream and institutionalize efficient
management of the supply chain for NTD medicines. They outline supply chain tasks and
responsibilities before, during and after MDA. They also present key considerations for
optimizing planning and implementation of supply chain activities in the country.

These procedures support the realization of the goal set in the WHO 2030 road map for
NTDs: an effective supply chain that ensures timely access to and availability of qualityassured medicines, products and pharmaceutical supplies at all levels and avoiding, e.g.
stockout, wastage, loss of tablets.

Target audience

The procedures are intended for use as a reference document by responsible persons and
key stakeholders of the NTD supply chain, as illustrated below.
Responsible persons and key stakeholders include both organizations and individuals.

• Organizations: Health ministries, national NTD programmes, central medical stores, national procurement
  and logistics agencies, regional and district medical stores, frontline health facilities,
  schools and national educational institutions.
• Individuals: National NTD programme staff and stakeholders, medical stores staff at all levels –
  pharmacists and warehouse managers, NTD focal persons and MDA supervisors,
  community health workers and community drug distributors.

 

 

Overview

WHO plays a major role in the cycle of supply chain management for donated and/or
procured health products for neglected tropical diseases (NTDs) amenable to preventive
chemotherapy and individual case management.
This first edition describes the standard operating procedures for health products for NTDs
amenable to preventive chemotherapy and the medicines donated to treat them. These
include albendazole for lymphatic filariasis and soil-transmitted helminthiases; azithromycin
for trachoma and yaws; diethylcarbamazine citrate for lymphatic filariasis; ivermectin for
onchocerciasis and lymphatic filariasis; mebendazole for soil-transmitted helminthiases;
praziquantel for schistosomiasis; and triclabendazole for foodborne trematodiases.
Standard operating procedures for diseases amenable to case management will be
covered in subsequent editions, including the application process for requesting medicines
(Chapter 1). In the meantime, the procedures described in the rest of the document apply
for both case management and preventive chemotherapy NTD health products.
WHO and the NTD Supply Chain Forum prepared this set of standard operating procedures
to reflect key characteristics in the supply chain management of health products including
donated medicines for use in mass drug administration (MDA) at the country level. Health
ministries and national programmes for NTDs are encouraged to adopt and adapt them to
their country context.

The role of the supply chain in MDA

MDA plays a role in the primary prevention of NTDs amenable to preventive chemotherapy
by decreasing transmission rates in populations at risk. The effectiveness of the MDA
strategy depends on epidemiological coverage, which is defined by WHO-recommended
targets for the proportion of the total population ingesting the medicines during MDA.
In order to meet the coverage targets the supply chain must be managed, from planning
and quantifying needs, to moving stock from production sites to patients at the service
delivery point to communities, schools and hospitals, among others, and to retrieving and
accounting for leftover stock, and all steps in between.

Objectives of these standard operating procedures

These standard operating procedures are intended to help strengthen the capacity of
health ministries and national NTD programmes to mainstream and institutionalize efficient
management of the supply chain for NTD medicines. They outline supply chain tasks and
responsibilities before, during and after MDA. They also present key considerations for
optimizing planning and implementation of supply chain activities in the country.

These procedures support the realization of the goal set in the WHO 2030 road map for
NTDs: an effective supply chain that ensures timely access to and availability of qualityassured medicines, products and pharmaceutical supplies at all levels and avoiding, e.g.
stockout, wastage, loss of tablets.

Target audience

The procedures are intended for use as a reference document by responsible persons and
key stakeholders of the NTD supply chain, as illustrated below.
Responsible persons and key stakeholders include both organizations and individuals.

• Organizations: Health ministries, national NTD programmes, central medical stores, national procurement
  and logistics agencies, regional and district medical stores, frontline health facilities,
  schools and national educational institutions.
• Individuals: National NTD programme staff and stakeholders, medical stores staff at all levels –
  pharmacists and warehouse managers, NTD focal persons and MDA supervisors,
  community health workers and community drug distributors.

 

 

Overview

WHO plays a major role in the cycle of supply chain management for donated and/or
procured health products for neglected tropical diseases (NTDs) amenable to preventive
chemotherapy and individual case management.
This first edition describes the standard operating procedures for health products for NTDs
amenable to preventive chemotherapy and the medicines donated to treat them. These
include albendazole for lymphatic filariasis and soil-transmitted helminthiases; azithromycin
for trachoma and yaws; diethylcarbamazine citrate for lymphatic filariasis; ivermectin for
onchocerciasis and lymphatic filariasis; mebendazole for soil-transmitted helminthiases;
praziquantel for schistosomiasis; and triclabendazole for foodborne trematodiases.
Standard operating procedures for diseases amenable to case management will be
covered in subsequent editions, including the application process for requesting medicines
(Chapter 1). In the meantime, the procedures described in the rest of the document apply
for both case management and preventive chemotherapy NTD health products.
WHO and the NTD Supply Chain Forum prepared this set of standard operating procedures
to reflect key characteristics in the supply chain management of health products including
donated medicines for use in mass drug administration (MDA) at the country level. Health
ministries and national programmes for NTDs are encouraged to adopt and adapt them to
their country context.

The role of the supply chain in MDA

MDA plays a role in the primary prevention of NTDs amenable to preventive chemotherapy
by decreasing transmission rates in populations at risk. The effectiveness of the MDA
strategy depends on epidemiological coverage, which is defined by WHO-recommended
targets for the proportion of the total population ingesting the medicines during MDA.
In order to meet the coverage targets the supply chain must be managed, from planning
and quantifying needs, to moving stock from production sites to patients at the service
delivery point to communities, schools and hospitals, among others, and to retrieving and
accounting for leftover stock, and all steps in between.

Objectives of these standard operating procedures

These standard operating procedures are intended to help strengthen the capacity of
health ministries and national NTD programmes to mainstream and institutionalize efficient
management of the supply chain for NTD medicines. They outline supply chain tasks and
responsibilities before, during and after MDA. They also present key considerations for
optimizing planning and implementation of supply chain activities in the country.

These procedures support the realization of the goal set in the WHO 2030 road map for
NTDs: an effective supply chain that ensures timely access to and availability of qualityassured medicines, products and pharmaceutical supplies at all levels and avoiding, e.g.
stockout, wastage, loss of tablets.

Target audience

The procedures are intended for use as a reference document by responsible persons and
key stakeholders of the NTD supply chain, as illustrated below.
Responsible persons and key stakeholders include both organizations and individuals.

• Organizations: Health ministries, national NTD programmes, central medical stores, national procurement
  and logistics agencies, regional and district medical stores, frontline health facilities,
  schools and national educational institutions.
• Individuals: National NTD programme staff and stakeholders, medical stores staff at all levels –
  pharmacists and warehouse managers, NTD focal persons and MDA supervisors,
  community health workers and community drug distributors.

 

 

Gainers

• Otonomy, Inc. OTIC shares surged 74.2% to $0.1866. Otonomy recently posted a Q3 loss of $0.18 per share.
• Apollo Endosurgery, Inc. APEN shares jumped 65% to $9.90 after the company announced it will be acquired by Boston Scientific for $10 per share in cash.
• The Very Good Food Company Inc. VGFC rose 36.6% to $0.1370.
• Kalera Public Limited Company KAL gained 29% to $0.16. Kalera announced restructuring process for German subsidiary.
• Kidpik Corp. PIK gained 25.6% to $0.98.
• Citi Trends, Inc. CTRN shares climbed 24.4% to $28.87 after the company reported better-than-expected Q3 adjusted EPS and sales results.
• Cosmos Holdings Inc. COSM jumped 23.3% to $0.7157 after jumping 35% on Monday.
• Bilibili Inc. BILI gained 23.2% to $15.52 after the company reported better-than-expected Q3 adjusted EPS and sales results.
• Zhihu Inc. ZH rose 20.3% to $1.0907 after declining over 9% on Monday.
• Faraday Future Intelligent Electric Inc. FFIE climbed 19.4% to $0.3626. Faraday Future Intelligent Electric Board of Directors has appointed FF China CEO Xuefeng (XF) Chen as Global CEO of the company, effective immediately.
• GDS Holdings Limited GDS shares rose 17.3% to $13.73. The company recently posted upbeat quarterly sales.
• NRx Pharmaceuticals, Inc. NRXP jumped 16.8% to $1.46.
• Vivakor, Inc. VIVK gained 16.6% to $1.1897 after posting a narrower quarterly loss.
• United Maritime Corporation USEA rose 16.3% to $3.5108. United Maritime declared a special cash dividend of $1.00 per share.
• ThermoGenesis Holdings, Inc. THMO surged 16% to $0.1371. ThermoGenesis Holdings recently posted a Q3 loss of $0.10 per share.
• Aenza S.A.A. AENZ jumped 15.8% to $2.3750.
• Fusion Fuel Green PLC HTOO gained 15.6% to $5.64. HC Wainwright & Co. maintained Fusion Fuel Green with a Buy and lowered the price target from $25 to $15.
• Kanzhun Limited BZ rose 15.3% to $17.41 after gaining over 5% on Monday.
• Dada Nexus Limited DADA gained 15% to $5.76. Shares of several Chinese companies traded higher amid hopes that protests in China could spark an easing of COVID restrictions.
• ThermoGenesis Holdings, Inc. THMO rose 14.2% to $0.1351. ThermoGenesis recently posted a Q3 loss of $0.10 per share.
• RLX Technology Inc. RLX gained 13.8% to $2.2086.
• The GEO Group, Inc. GEO surged 12% to $11.45 following positive analyst coverage from Wedbush.
• Kingsoft Cloud Holdings Limited KC gained 11.6% to $2.6350. Shares of several Chinese companies traded higher amid hopes that protests in China could spark an easing of COVID restrictions.
• Eqonex Limited EQOS rose 10.9% to $0.1562.
• HUYA Inc. HUYA gained 10.9% to $ 2.2850. Shares of several Chinese companies traded higher amid hopes that protests in China could spark an easing of COVID restrictions.
• XPeng Inc. XPEV climbed 10.2% to $7.59. Shares of several Chinese companies traded higher amid hopes that protests in China could spark an easing of COVID restrictions.
• JD.com, Inc. JD gained 8.4% to $54.19. JD.com is looking to lower pay by up to 20% for senior executives, according to Financial Times.
• JOYY Inc. YY rose 7.2% to $29.50 following upbeat quarterly earnings.

 

Losers

• MICT, Inc. MICT fell 28.3% to $0.81 after dropping 13% on Monday. MICT said that the company is targeting a considerable share repurchase program post-merger close
• Alaunos Therapeutics, Inc. TCRT shares fell 24.2% to $0.6575 after the company reported pricing of public offering of common stock.
• Satixfy Communications Ltd. SATX dropped 17.4% to $16.82.
• Enfusion, Inc. ENFN declined 16.7% to $10.24. Enfusion announced resignation of chief financial officer and reiterated Q4 and FY22 outlook.
• Digital Brands Group, Inc. DBGI declined 15.9% to $6.05.
• ASAP, Inc. ASAP fell 15.7% to $0.9101. ASAP.com & Chipotle Mexican Grill signed major food delivery agreement.
• NanoVibronix, Inc. NAOV shares fell 15.5% to $0.5349 after the company announced a $2.4 million registered direct offering priced at-the-market under Nasdaq rules.
• AGBA Group Holding Limited AGBA fell 14.5% to $2.94.
• FOXO Technologies Inc. FOXO fell 13.8% to $0.4785 after dropping around 10% on Monday.
• Coeptis Therapeutics Holdings, Inc. COEP shares fell 13.7% to $1.7699.
• CinCor Pharma, Inc. CINC fell 13.4% to $12.23. Oppenheimer downgraded CinCor Pharma from Outperform to Perform, while Morgan Stanley downgraded the stock from Overweight to Equal-Weight and lowered the price target from $60 to $22.
• Hibbett, Inc. HIBB fell 12.2% to $59.33 after the company reported worse-than-expected Q3 EPS and sales results.
• CNS Pharmaceuticals, Inc. CNSP fell 11.7% to $4.4250. CNS Pharmaceuticals announced a 1-for-30 reverse stock split.
• Ainos, Inc. AIMD declined 11.6% to $0.6101. Ainos posted Q3 loss of $0.51 per share.
• Nutex Health Inc. NUTX dropped 10.3% to $1.39.
• Elbit Systems Ltd. ESLT fell 9.2% to $169.67 after the company reported a drop in profit for the third quarter.
• Sprout Social, Inc. SPT dipped 7.7% to $53.40.

© 2022 Benzinga.com. Benzinga does not provide investment advice. All rights reserved.

Gainers

• Otonomy, Inc. OTIC shares surged 74.2% to $0.1866. Otonomy recently posted a Q3 loss of $0.18 per share.
• Apollo Endosurgery, Inc. APEN shares jumped 65% to $9.90 after the company announced it will be acquired by Boston Scientific for $10 per share in cash.
• The Very Good Food Company Inc. VGFC rose 36.6% to $0.1370.
• Kalera Public Limited Company KAL gained 29% to $0.16. Kalera announced restructuring process for German subsidiary.
• Kidpik Corp. PIK gained 25.6% to $0.98.
• Citi Trends, Inc. CTRN shares climbed 24.4% to $28.87 after the company reported better-than-expected Q3 adjusted EPS and sales results.
• Cosmos Holdings Inc. COSM jumped 23.3% to $0.7157 after jumping 35% on Monday.
• Bilibili Inc. BILI gained 23.2% to $15.52 after the company reported better-than-expected Q3 adjusted EPS and sales results.
• Zhihu Inc. ZH rose 20.3% to $1.0907 after declining over 9% on Monday.
• Faraday Future Intelligent Electric Inc. FFIE climbed 19.4% to $0.3626. Faraday Future Intelligent Electric Board of Directors has appointed FF China CEO Xuefeng (XF) Chen as Global CEO of the company, effective immediately.
• GDS Holdings Limited GDS shares rose 17.3% to $13.73. The company recently posted upbeat quarterly sales.
• NRx Pharmaceuticals, Inc. NRXP jumped 16.8% to $1.46.
• Vivakor, Inc. VIVK gained 16.6% to $1.1897 after posting a narrower quarterly loss.
• United Maritime Corporation USEA rose 16.3% to $3.5108. United Maritime declared a special cash dividend of $1.00 per share.
• ThermoGenesis Holdings, Inc. THMO surged 16% to $0.1371. ThermoGenesis Holdings recently posted a Q3 loss of $0.10 per share.
• Aenza S.A.A. AENZ jumped 15.8% to $2.3750.
• Fusion Fuel Green PLC HTOO gained 15.6% to $5.64. HC Wainwright & Co. maintained Fusion Fuel Green with a Buy and lowered the price target from $25 to $15.
• Kanzhun Limited BZ rose 15.3% to $17.41 after gaining over 5% on Monday.
• Dada Nexus Limited DADA gained 15% to $5.76. Shares of several Chinese companies traded higher amid hopes that protests in China could spark an easing of COVID restrictions.
• ThermoGenesis Holdings, Inc. THMO rose 14.2% to $0.1351. ThermoGenesis recently posted a Q3 loss of $0.10 per share.
• RLX Technology Inc. RLX gained 13.8% to $2.2086.
• The GEO Group, Inc. GEO surged 12% to $11.45 following positive analyst coverage from Wedbush.
• Kingsoft Cloud Holdings Limited KC gained 11.6% to $2.6350. Shares of several Chinese companies traded higher amid hopes that protests in China could spark an easing of COVID restrictions.
• Eqonex Limited EQOS rose 10.9% to $0.1562.
• HUYA Inc. HUYA gained 10.9% to $ 2.2850. Shares of several Chinese companies traded higher amid hopes that protests in China could spark an easing of COVID restrictions.
• XPeng Inc. XPEV climbed 10.2% to $7.59. Shares of several Chinese companies traded higher amid hopes that protests in China could spark an easing of COVID restrictions.
• JD.com, Inc. JD gained 8.4% to $54.19. JD.com is looking to lower pay by up to 20% for senior executives, according to Financial Times.
• JOYY Inc. YY rose 7.2% to $29.50 following upbeat quarterly earnings.

 

Losers

• MICT, Inc. MICT fell 28.3% to $0.81 after dropping 13% on Monday. MICT said that the company is targeting a considerable share repurchase program post-merger close
• Alaunos Therapeutics, Inc. TCRT shares fell 24.2% to $0.6575 after the company reported pricing of public offering of common stock.
• Satixfy Communications Ltd. SATX dropped 17.4% to $16.82.
• Enfusion, Inc. ENFN declined 16.7% to $10.24. Enfusion announced resignation of chief financial officer and reiterated Q4 and FY22 outlook.
• Digital Brands Group, Inc. DBGI declined 15.9% to $6.05.
• ASAP, Inc. ASAP fell 15.7% to $0.9101. ASAP.com & Chipotle Mexican Grill signed major food delivery agreement.
• NanoVibronix, Inc. NAOV shares fell 15.5% to $0.5349 after the company announced a $2.4 million registered direct offering priced at-the-market under Nasdaq rules.
• AGBA Group Holding Limited AGBA fell 14.5% to $2.94.
• FOXO Technologies Inc. FOXO fell 13.8% to $0.4785 after dropping around 10% on Monday.
• Coeptis Therapeutics Holdings, Inc. COEP shares fell 13.7% to $1.7699.
• CinCor Pharma, Inc. CINC fell 13.4% to $12.23. Oppenheimer downgraded CinCor Pharma from Outperform to Perform, while Morgan Stanley downgraded the stock from Overweight to Equal-Weight and lowered the price target from $60 to $22.
• Hibbett, Inc. HIBB fell 12.2% to $59.33 after the company reported worse-than-expected Q3 EPS and sales results.
• CNS Pharmaceuticals, Inc. CNSP fell 11.7% to $4.4250. CNS Pharmaceuticals announced a 1-for-30 reverse stock split.
• Ainos, Inc. AIMD declined 11.6% to $0.6101. Ainos posted Q3 loss of $0.51 per share.
• Nutex Health Inc. NUTX dropped 10.3% to $1.39.
• Elbit Systems Ltd. ESLT fell 9.2% to $169.67 after the company reported a drop in profit for the third quarter.
• Sprout Social, Inc. SPT dipped 7.7% to $53.40.

© 2022 Benzinga.com. Benzinga does not provide investment advice. All rights reserved.

Gainers

• Taboola.com Ltd. TBLA shares gained 52.5% to $2.8050 after the company announced it entered into a 30-year exclusive commercial agreement with Yahoo.
• Digital Brands Group, Inc. DBGI shares jumped 47.8% to $8.81. The company recently posted a rise in Q3 revenue.
• NanoVibronix, Inc. NAOV gained 39% to $0.3599. NanoVibronix recently announced interim results of its U.K. clinical study for UroShield, a disposable ultrasound device that reduces biofilm contaminating the catheter surface.
• Talkspace, Inc. TALK shares climbed 34.3% to $0.8055. Talkspace recently named Jon Cohen as CEO.
• Studio City International Holdings Limited MSC gained 33% to $2.70.
• Helbiz, Inc. HLBZ rose 31.8% to $0.3032 after gaining more than 21% on Friday.
• Axsome Therapeutics, Inc. AXSM climbed 31.4% to $74.71 after the company announced AXS-05 achieved its primary endpoint in the ACCORD Phase 3 trial in Alzheimer’s disease agitation.
• Tricida, Inc. TCDA rose 25.3% to $0.2577 after gaining over 6% on Friday.
• Kintara Therapeutics, Inc. KTRA shares gained 23% to $4.5375 after the company announced it was granted Fast Track Designation from the FDA for REM-001 for cutaneous Metastatic Breast Cancer.
• So-Young International Inc. SY jumped 21% to $0.7705. The company recently posted downbeat quarterly sales.
• Bit Brother Limited BTB gained 19.2% to $0.26.
• Katapult Holdings, Inc. KPLT gained 18.8% to $1.14. Katapult recently appointed Nancy Walsh as new CFO.
• Cosmos Holdings Inc. COSM surged 18.4% to $0.5077.
• Recruiter.com Group, Inc. RCRT rose 17.4% to $0.4345. Recruiter.com Group, on November 18th, said it received a notification letter from the Nasdaq Listing Qualifications Staff of the Nasdaq Stock Market LLC.
• Biophytis S.A. BPTS gained 16.3% to $0.4472.
• Centogene N.V. CNTG jumped 15.7% to $0.88. HC Wainwright & Co. recently initiated coverage on Centogene with a Buy rating and announced a price target of $2.5.
• Pinduoduo Inc. PDD gained 14% to $75.03. Pinduoduo reported third-quarter FY22 revenue growth of 65% year-on-year to $4.99 billion, beating the consensus of $4.31 billion.
• Standard BioTools Inc. LAB surged 13.8% to $1.48. Standard BioTools authorized up to $20 million in share repurchases.
• HUTCHMED (China) Limited HCM gained 12.4% to $12.03.
• The Singing Machine Company, Inc. MICS shares rose 12.3% to $6.17. Singing Machine recently posted Q2 EPS of $0.08.
• BiomX Inc. PHGE jumped 11.5% to $0.28. The company recently posted a narrower quarterly loss.
• Lion Group Holding Ltd. LGHL gained 11.4% to $1.27.
• Abcam plc ABCM rose 10.2% to $17.48. NanoString and Abcam recently expanded collaboration to advance spatial multiomics research.
• American Rebel Holdings, Inc. AREB rose 9.7% to $0.2843 after gaining over 8% on Friday. The company recently posted a narrower quarterly loss.
• Tencent Music Entertainment Group TME gained 8.7% to $6.28. JP Morgan recently upgraded Tencent Music Enter from Neutral to Overweight and raised the price target from $4.8 to $7.7.
• Dada Nexus Limited DADA gained 6.8% to $4.97.
• Univar Solutions Inc. UNVR rose 5.2% to $32.62 after the company confirmed preliminary indication of interest from Brenntag SE.

Losers

• CinCor Pharma, Inc. CINC shares dipped 46.9% to $14.08 after the company announced topline data for the Phase 2 HALO trial evaluating Baxdrostat in uncontrolled hypertension. HALO did not achieve statistical significance on its primary endpoint.
• OncoSec Medical Incorporated ONCS fell 22.6% to $2.60. OncoSec Medical recently announced early clinical data from an investigator-sponsored trial of TAVO in combination with Bristol-Myers Squibb Co’s BMY intravenous Opdivo (nivolumab).
• Troika Media Group, Inc. TRKA dropped 21.4% to $0.1831.
• TC Biopharm (Holdings) Plc TCBP dipped 21% to $5.30 after the company announced a $7.35 million private placement.
• Golden Sun Education Group Limited GSUN fell 18% to $1.6901.
• EUDA Health Holdings Limited EUDA dropped 17.6% to $3.0401.
• Anavex Life Sciences Corp. AVXL fell 17.3% to $9.83 after the company reported worse-than-expected Q4 EPS results.
• Bioventus Inc. BVS fell 15.5% to $2.0712. The company recently posted downbeat quarterly results.
• Evolve Transition Infrastructure LP SNMP dropped 15.5% to $0.1521.
• Peraso Inc. PRSO declined 15.4% to $1.15. Peraso announced a $2.45 million registered direct offering.
• Peak Bio, Inc. PKBO dropped 14.8% to $5.42.
• Scilex Holding Company SCLX shares fell 14.6% to $4.11.
• TransCode Therapeutics, Inc. RNAZ dipped 13.7% to $0.4140. TransCode Therapeutics filed for offering of up to 12.5 million shares of common stock on firm commitment basis.
• Expion360 Inc. XPON dropped 13.6% to $1.27. Expion360 recently posted a Q3 loss of $0.19 per share.
• Grindr Inc. GRND fell 13.4% to $8.27.
• Community Health Systems, Inc. CYH fell 13% to $3.1150.
• The Hain Celestial Group, Inc. HAIN dipped 12.6% to $18.05. Hain Celestial Group appointed Wendy P. Davidson as President and Chief Executive Officer, effective January 1, 2023.
• Satixfy Communications Ltd. SATX fell 11.7% to $20.21.
• Brenmiller Energy Ltd BNRG fell 11.7% to $1.5101 after jumping 14% on Friday.
• Fluence Energy, Inc. FLNC dropped 11.5% to $16.42.
• NewAmsterdam Pharma Company N.V. NAMS shares fell 10.6% to $9.00.
• Prime Medicine, Inc. PRME dipped 10.2% to $18.60.
• Polestar Automotive Holding UK PLC PSNY dropped 8.8% to $7.29.
• Check-Cap Ltd. CHEK dipped 8.8% to $3.5005.
• Cyxtera Technologies, Inc. CYXT fell 8.7% to $1.7050.
• DraftKings Inc. DKNG fell 3.7% to $14.59. JP Morgan downgraded DraftKings from Neutral to Underweight and announced $12 price target.

© 2022 Benzinga.com. Benzinga does not provide investment advice. All rights reserved.

Overview

WHO plays a major role in the cycle of supply chain management for donated and/or
procured health products for neglected tropical diseases (NTDs) amenable to preventive
chemotherapy and individual case management.
This first edition describes the standard operating procedures for health products for NTDs
amenable to preventive chemotherapy and the medicines donated to treat them. These
include albendazole for lymphatic filariasis and soil-transmitted helminthiases; azithromycin
for trachoma and yaws; diethylcarbamazine citrate for lymphatic filariasis; ivermectin for
onchocerciasis and lymphatic filariasis; mebendazole for soil-transmitted helminthiases;
praziquantel for schistosomiasis; and triclabendazole for foodborne trematodiases.
Standard operating procedures for diseases amenable to case management will be
covered in subsequent editions, including the application process for requesting medicines
(Chapter 1). In the meantime, the procedures described in the rest of the document apply
for both case management and preventive chemotherapy NTD health products.
WHO and the NTD Supply Chain Forum prepared this set of standard operating procedures
to reflect key characteristics in the supply chain management of health products including
donated medicines for use in mass drug administration (MDA) at the country level. Health
ministries and national programmes for NTDs are encouraged to adopt and adapt them to
their country context.

The role of the supply chain in MDA

MDA plays a role in the primary prevention of NTDs amenable to preventive chemotherapy
by decreasing transmission rates in populations at risk. The effectiveness of the MDA
strategy depends on epidemiological coverage, which is defined by WHO-recommended
targets for the proportion of the total population ingesting the medicines during MDA.
In order to meet the coverage targets the supply chain must be managed, from planning
and quantifying needs, to moving stock from production sites to patients at the service
delivery point to communities, schools and hospitals, among others, and to retrieving and
accounting for leftover stock, and all steps in between.

Objectives of these standard operating procedures

These standard operating procedures are intended to help strengthen the capacity of
health ministries and national NTD programmes to mainstream and institutionalize efficient
management of the supply chain for NTD medicines. They outline supply chain tasks and
responsibilities before, during and after MDA. They also present key considerations for
optimizing planning and implementation of supply chain activities in the country.

These procedures support the realization of the goal set in the WHO 2030 road map for
NTDs: an effective supply chain that ensures timely access to and availability of qualityassured medicines, products and pharmaceutical supplies at all levels and avoiding, e.g.
stockout, wastage, loss of tablets.

Target audience

The procedures are intended for use as a reference document by responsible persons and
key stakeholders of the NTD supply chain, as illustrated below.
Responsible persons and key stakeholders include both organizations and individuals.

• Organizations: Health ministries, national NTD programmes, central medical stores, national procurement
  and logistics agencies, regional and district medical stores, frontline health facilities,
  schools and national educational institutions.
• Individuals: National NTD programme staff and stakeholders, medical stores staff at all levels –
  pharmacists and warehouse managers, NTD focal persons and MDA supervisors,
  community health workers and community drug distributors.